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KMID : 0857020140290020125
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Kosin Medical Journal
2014 Volume.29 No. 2 p.125 ~ p.134
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The Change of Thyroid Stimulating Hormone Values of Healthy Subjects According to Temperature and Aging
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Kim Sung-Su
Lew Dong-Hoon
Choi Ja-Yoon
Lee Eun-Ju
Kim Min-Kyo
Kim Kyong-Young
Kim Soo-Kyoung
Jung Jung-Hwa
Jung Jae-Hoon
Hahm Jong-Ryeal
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Abstract
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Objective: We conducted a study to investigate the normal range for TSH and within-individual variations of TSH according to temperature and aging.
Patients and Methods:
We enrolled patients who underwent periodic medical examinations five times over a six year period (2007.8~2013.6). Anthropometric data and thyroid ultrasonography were evaluated, and serum TSH, T3, and T4 were assayed.
Results: Subjects were 19-64 years old, 120 were female, and 208 were male. Reference ranges for TSH were 0.53-4.94 mIU/L in the first test, 0.49-5.61 mIU/L in the second test, 0.46-6.06 mIU/L in the third test, 0.48-5.99 mIU/L in the fourth test, and 0.52-6.3 mIU/L in the fifth test. When the TSH level was analyzed according to temperature and sex, mean TSH was higher in months in which the average monthly temperatures were below 10℃ in Jinju, Gyeongnam and female. The aging and low temperatures are associated with increased serum TSH concentrations in the within-individual.
Conclusions: This study showed that aging is associated with increased serum TSH concentrations in the within-individual and serum TSH concentrations are different in the within-individual according to the temperature.
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KEYWORD
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Reference range for TSH, TSH, Variation of TSH
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